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pentobarbital will lower the extent or effect of parecoxib by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Monitor.pentobarbital will decrease the extent or effect of atogepant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Proposed atogepant dosage with concomitant usage of powerful or